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Low-density lipoprotein cholesterol levels were increased in monophasic levonorgestrel and clearly decreased in the lowest ethinyl estradiol-containing monophasic desogestrel (150/20) and biphasic desogestrel preparations. The monophasic desogestrel (150/30) and biphasic desogestrel preparations induced higher high-density lipoprotein cholesterol and apolipoprotein A-I levels than did their levonorgestrel-containing antibiotics pharmacy online drugstore counterparts. contraceptives The differences seen between the desogestrel and levonorgestrel preparations can best be explained by the lower intrinsic androgenicity of 3-keto-desogestrel (active metabolite contraceptives of desogestrel) than that of levonorgestrel.. Phase 1 comprised of 6 brown tablets, each containing 0.050 mg of levonorgestrel, a totally synethic progestogen, and 0.030 mg of ethinyl estradiol; phase 2 comprised of 5 white tablets, each containing 0.075 mg levongestrel and 0.040 mg ethinyl estradiol; phase 3 comprised of 10 light-yellow tablets, each containing 0.125 mg levongestrel and 0.030 mg ethinyl estradiol. The following preparations were studied. (1) monophasic desogestrel (150/30), (2) monophasic desogestrel (150/20, containing 20 micrograms of ethinyl estradiol instead of 30 micrograms of alesse ethinyl estradiol, (3) biphasic desogestrel, (4) monophasic levonorgestrel (150/30), and (5) triphasic levonorgestrel. Effects of three combined oral contraceptive preparations containing desogestrel plus ethinyl estradiol on lipid metabolism in comparison with two levonorgestrel preparations.The effects of three different desogestrel-containing combined oral contraceptive preparations on lipid transfiguration were compared with those of two levonorgestrel preparations. The effects of these preparations were assessed on high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, apolipoprotein A-I, apolipoprotein B, the ratio of high-density lipoprotein cholesterol to low-density lipoprotein cholesterol, and the ratio of apolipoprotein A-I to apolipoprotein B after 3 months of treatment, and the percentage changes with regard to pretreatment were calculated. Apolipoprotein B increased in all preparations. Triphasil is a "triphasic" oral knuckle guard pill. This means that the hormones contained in the tablets are delivered in three stages.Each Triphasil cycle of 21 tablets consists of three different drug phases as follows. The antiatherogenic indexes (ratios of high-density lipoprotein cholesterol to low-density lipoprotein cholesterol and apolipoprotein A-I to apolipoprotein B were higher for monophasic desogestrel (150/30) and biphasic desogestrel than for comparable levonorgestrel-containing preparations.
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